Volume 26, Number 3

Generalized Anxiety Disorder: Diagnostic and Treatment Issues
Nearly 1 in 5 individuals with lifetime major depressive disorder (MDD) are diagnosed with comorbid generalized anxiety (GAD), and likewise 90% of GAD patients have a comorbid psychiatric diagnosis. The authors discuss the prevalence of GAD, including keys to its diagnosis and the latest treatment options. Read More

Hippocampus and Unipolar Depression
This meta-analysis supports considerable evidence that links depression to a reduction in the volume of the hippocampus, the area of the brain associated with cognitive processes, memory and stress response regulation. The author examines the effect of hippocampal abnormalities in both neurology and psychology, and also what treatments may help to stabilize its functioning. Read More

Behavioral, Psychosocial, and Pharmacologic Interventions in Adults with Developmental Disabilities
The authors dissect the challenge of treating adult patients with developmental disabilities and comorbid psychophathology, including psychiatric disorders, mental retardation, and behavioral problems. The emphasis here is distinguishing between coexisting disabilities and adopting evidence-based strategies to treat them most effectively. Read More

The Efficacy and Tolerability of Atypical Compared with Typical Neuroleptics in Schizophrenia
Authored by pioneers in the field of psychopharmacology, the review offers a clear and comprehensive comparison of the efficacy and side-effect profile of atypical versus typical neuroleptics used in the treatment of schizophrenia. The challenges of treating this disorder merits a summary of this kind, which focuses on minimizing side-effects and maximizing cost-effectiveness for patients. Read More

Methamphetamine Abuse and Dependence: An Update
There's no doubt that crystal meth abuse is on the rise; it's easy and inexpensive to produce and widely available. It is also one of the most physiologically and psychologically damaging of all illicit substances. The purpose of this update is to give clinicians a historical overview of methamphetamine abuse and to report on the latest treatment options for this epidemic. Read More

The Effects of Amphetamine Use During Pregnancy and Lactation
Amphetamine use is not without risk, but never so much as during pregnancy or while breastfeeding. In this review, the authors compile data from several studies providing the deleterious effects of amphetamines on the fetus, neonate, and pregnant mother of both animals and humans. Read More